BAMM PUBLICATIONS

Chemical-Protective Gloves for Acrylic Acid and the Basic Acrylic Esters (n-Butyl Acrylate, Ethyl Acrylate, Ethylhexyl Acrylate, Hydroxyethyl Acrylate, Hydroxypropyl Acrylate, and Methyl Acrylate) - March 2006

ACRYLIC ACID Background Document (CAS NUMBER 79-10-7) - Last Updated - April 2006

ACRYLATE ESTERS Background Document - Last Updated 2000

"Understanding Chemical Odors in Your Community"

"Fact Sheet: Acrylic Acid and the Basic Acrylic Esters"

BAMM member scientists have written a book published by CRC Press which discusses toxicology information regarding acrylic acid and its esters. Following is an excerpt from that book.

These chemicals are reactive monomers which are employed as intermediates in the manufacture of useful, and in many cases essential, polymers and plastics. It is the chemical reactivity that makes these monomers useful in polymer production and also of concern because of possible biological reactivity resulting in toxic responses. Health Effect Assessments of the Basic Acrylates is the first book which provides a comprehensive compilation of toxicological and ecotoxicological effects of the five major high-production volume acrylates:: acrylic acid, methyl acrylate, ethyl acrylate, butyl acrylate, and 2-ethylhexyl acrylate. In addition, the authors of each chapter offer insightful interpretations of these effects and their relevance to man and the environment.

For each of these monomers, perspective is given to the severity of observed toxic responses. The nature of the responses are discussed in relationship to the metabolism and biological reactivity of the acid and each of the esters. Current areas of investigative toxicology, as they apply to these chemicals, are then critically reviewed. Thus, the mechanism of forestomach tumor formation and the meaning of this response in the absence of any other type of carcinogenic response and a lack of genotoxic activity are discussed. The role of irritation in toxic responses is also evaluated.

Each chapter in this book stands alone as a complete review of the respective monomers. The book is comprehensively referenced and indexed. As such, this book should, for many years, remain the standard reference for obtaining and understanding the considerable health effects information on the basic acrylates.

Excerpt from: "Health Effect Assessments of the Basic Acrylates." Tyler, T.R., et al, 1993, CRC Press, Inc., 2000 Corporate Blvd., N.W., Boca Raton, FL 33431.

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